Mitomycin

(Mitomycin)

Antitumor antibiotic

At a Glance

  • To prevent scar tissue and urethral stricture recurrence post-surgery
  • Inhibits fibroblast proliferation and DNA synthesis at the surgical site
  • Local injection or topical application (not systemic chemotherapy)
  • Reduces recurrence of urethral strictures
  • Minimizes post-op scar formation
  • Enhances long-term surgical outcomes

The Details

Mitomycin is a chemotherapy agent used off-label in urology to help prevent scar tissue formation after procedures like urethrotomy. When applied locally, it slows fibroblast activity and reduces recurrence of strictures by minimizing scarring at the surgical site.

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